NEET 2001 Biology question

Sickle cell anaemia is due to : -

(1)Change of Amino Acid in -chain of Haemoglobin
(2)Change of Amino Acid in -chain of HaemoglobinCorrect
(3)Change of Amino acid in both and chain of Haemoglobin
(4)Change of Amino acid either or chain

Answer: (2)

Solution

Sickle cell anaemia is an autosomal recessive disease caused by a point (base-substitution) mutation in the gene for the beta-globin chain of haemoglobin: GAG changes to GTG, so glutamic acid

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Question ID VK-088921