NEET 2006 Biology question

Angiotensinogen is a protein produced and secreted by-

(1)Macula densa cells
(2)Endothelial cells (cells lining the blood vessels)
(3)Liver cellsCorrect
(4)Juxtaglomerular (JG) cells

Answer: (3)

Solution

Angiotensinogen is a plasma protein (an alpha-2 globulin) synthesised and secreted continuously by the liver (hepatocytes). When blood pressure/flow in the kidney falls, the juxtaglomerular (JG) cells secrete renin, which converts angiotensinogen

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Question ID VK-089734