NEET 2008 Biology question

Which one of the following conditions in humans is correctly matched with its chromosomal abnormality/linkage?

(1)Down syndrome - 44 autosomes + XO
(2)Klinefelter syndrome - 44 autosomes + XXYCorrect
(3)Colour blindness - Y-linked
(4)Erythroblastosis foetalis - X-linked

Answer: (2)

Solution

Klinefelter syndrome is due to an extra X chromosome in males: karyotype 44 autosomes + XXY (47 chromosomes). Hence option (2). (1) Down syndrome is trisomy 21 (45 autosomes + XX/XY); 44

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Question ID VK-090056