NEET 2008 Biology question

Not in NEET syllabus

What will happen if the secretion of parietal cells of gastric glands is blocked with an inhibitor?

(1)Enterokinase will not be released from the duodenal mucosa and so trypsinogen is not converted to trypsin
(2)Gastric juice will be deficient in chymosin
(3)Gastric juice will be deficient in pepsinogen
(4)In the absence of HCl secretion, inactive pepsinogen is not converted into the active enzyme pepsin.Correct

Answer: (4)

Solution

Parietal (oxyntic) cells of the gastric glands secrete HCl and the intrinsic factor. HCl provides the acidic pH (about 1.8) that converts inactive pepsinogen into active pepsin; if HCl secretion is blocked, pepsinogen cannot be activated. Hence option (4). (1) Enterokinase is

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Question ID VK-090086