NEET 2012 Biology question

Which one of the following represents palindromic sequence in DNA ?

(1)5' - GATACC - 3' / 3' - CCTAAG - 5'
(2)5' - GAATTC - 3' / 3' - CTTAAG - 5'Correct
(3)5' - CCAATG - 3' / 3' - GAATCC - 5'
(4)5' - CATTAG - 3' / 3' - GATAAC - 5'

Answer: (2)

Solution

A palindromic sequence is a stretch of double-stranded DNA in which the base sequence read 5' to 3' is the same on both strands. For GAATTC (top strand, 5' to 3') the complementary strand 3'-CTTAAG-5' reads 5'-GAATTC-3' too, so it is a palindrome. This is the recognition site of the

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Question ID VK-091030