NEET 2026 Biology question

Biology Principles of Inheritance and Variation NEET 2026

Which one of the following disorders is caused by the substitution of Glutamic acid (Glu) by Valine (Val) at the sixth position of the beta globin chain of the haemoglobin molecule?

(1)Thalassemia
(2)Sickle-cell anaemiaCorrect
(3)Phenylketonuria
(4)Haemophilia

Answer: (2)

Solution

Sickle-cell anaemia is an autosomal recessive disorder caused by a point mutation (GAG to GUG in mRNA) that replaces glutamic acid by valine at the sixth position of the beta-globin chain of haemoglobin

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Question ID VK-104941