NEET Biology question

With the help of the following, identify the correct sequence, that leads to the formation of blood clot. I. Blood clot II. Injury III. Factor II IV. Factor III V. Factor IV VI. Fibrinogen VII. Thrombin

(A)II → III → IV → VI → VII → I
(B)II → III → VII → VI → ICorrect
(C)II → IV → III → VII → VI → I (Factor III and Factor IV act as inputs converting Factor II to Thrombin)
(D)II → IV → III → VI → VII → I (Factor III and Factor IV act as inputs converting Factor II to Thrombin)

Answer: (B)

Solution

Following an injury (II), the main chain of the clotting cascade proceeds as: prothrombin, Factor II (III) is converted into its active form, thrombin (VII) — with thromboplastin (Factor III) and Ca²⁺ (Factor IV) acting as necessary cofactors/inputs into this step rather than as sequential links themselves — and

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Question ID VK-110899