Which of the following sequences is correct regarding regulation of kidney function?
(A)An excess loss of water from body → Hypothalamus → Osmoreceptors → Neurohypophysis → ADH → Increases water permeability of DCT and CT → Prevention of diuresis
(B)An excess loss of fluid from body → Osmoreceptors → Hypothalamus → Neurohypophysis → ADH → Increases water permeability of DCT and CT → Prevention of diuresisCorrect
(C)An excess loss of fluid from body → Osmoreceptors → Hypothalamus → Neurohypophysis → Aldosterone → Water permeability of DCT increases → Prevention of diuresis
(D)An excess loss of fluid from body → Osmoreceptors → Hypothalamus → Adenohypophysis → ADH → Increases water permeability of DCT and CT → Prevention of diuresis
Answer: (B)
Solution
An excess loss of body fluid is first detected by the osmoreceptors, which then signal the hypothalamus; the hypothalamus triggers release of ADH from the neurohypophysis (posterior pituitary), which increases the water permeability of the DCT and collecting tubule, preventing
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