NEET Biology question
I. Myotonic dystrophy is an autosomal dominant trait; II. Sickle-cell anaemia is an autosomal recessive trait; III. Failure of segregation of alleles results in chromosomal loss; IV. Failure of segregation of allele result in chromosomal gain; V. Cystic fibrosis is a Mendelian disorder. Correct statements are
Answer: (D)
Solution
Myotonic dystrophy is indeed an autosomal dominant trait (I), sickle-cell anaemia is an autosomal recessive disease (II), and cystic fibrosis is a classic Mendelian disorder (V); when alleles (carried on sister chromatids or homologous chromosomes) fail to segregate properly during cell division, one
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