NEET Biology question

Which one of the following conditions, though harmful in itself, is also a potential saviour from a mosquito-borne infectious disease?

(A)Thalassaemia
(B)Sickle cell anaemiaCorrect
(C)Pernicious anaemia
(D)Leukaemia

Answer: (B)

Solution

Sickle-cell anaemia results from a point mutation causing glutamic acid to be replaced by valine at the 6th position of the haemoglobin β-chain. Although this causes harmful sickling of red blood cells, carriers (heterozygotes) are significantly protected from malaria (a mosquito-borne disease caused by *Plasmodium*),

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Question ID VK-120177