NEET Biology question

Sickle cell anaemia is induced by

(A)Change of amino acid in the -chain of haemoglobin
(B)Change of amino acid in the -chain of haemoglobinCorrect
(C)Change of amino acid in both and chains of haemoglobin
(D)Change of amino acid in either the or chain of haemoglobin

Answer: (B)

Solution

Sickle-cell anaemia results from a point mutation specifically in the gene encoding the β-globin chain of haemoglobin, causing the 6th amino acid, glutamic acid, to be replaced by valine (HbA → HbS). This structural change

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Question ID VK-120219