NEET Biology question

Why is *Bt* toxin not toxic to human beings?

(A)The toxin recognises only insect specific targets
(B)*Bt* toxin activation requires temperature above the human body temperature
(C)*Bt* toxin formation from pro-*Bt* state which requires pH lower than that present in human stomach
(D)Conversion of pro-*Bt* toxin to *Bt* toxin takes place only in highly alkaline conditionsCorrect

Answer: (D)

Solution

The protoxin crystal of *Bt* toxin requires a highly alkaline environment, as found in the insect gut, to be solubilised and converted into its active toxic form, and since the human stomach is

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Question ID VK-125618