NEET Biology question

BiologyBiotechnology and Its ApplicationsNEET

Which of the following is/are correct about Adenosine Deaminase (ADA) deficiency? I. In the absence of adenosine deaminase enzyme, purine metabolism is disturbed and T-lymphocytes fail to function II. ADA deficiency is caused by the deletion of the gene for ADA III. In some cases, it can be cured by bone marrow transplantation and enzyme replacement therapy, but in both approaches the patients are not completely cured IV. For permanent cure, genes isolated from the bone marrow cells producing ADA at early embryonic stages can be a possible cure Which of the statements given above are correct?

Answer: (D)

Solution

All four statements correctly describe ADA deficiency and its management as taught in the standard syllabus: in the absence of ADA, purine metabolism is disturbed and T-lymphocytes fail to function (I); ADA deficiency is attributed to deletion of the gene for adenosine

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Question ID VK-125634