NEET Biology question

Which step was proved to be the main challenge in the production of human insulin by recombinant DNA technology?

(A)Splitting A and B-peptide chains
(B)Addition of C-peptide to proinsulin
(C)Getting insulin assembled into mature formCorrect
(D)Removal of C-peptide from active insulin

Answer: (C)

Solution

Because bacteria produce the A- and B-chains separately without the natural proinsulin folding process, the real challenge was getting these separately

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Question ID VK-125650