JEE Main Chemistry question

Thyroxine, a thyroid hormone that helps regulate metabolic rate, is formed from a diphenyl ether-linked tyrosine-type amino acid framework upon iodination (, ). Thyroxine is:

(A)[diphenyl ether structure with two iodine substituents total]
(B)[diphenyl ether structure with four iodine substituents total, two on each ring, ortho to the ether linkage]Correct
(C)[diphenyl ether structure with four iodine substituents in an alternative arrangement]
(D)[diphenyl ether structure with six iodine substituents total]

Answer: (B)

Solution

Thyroxine is chemically known as tetraiodothyronine () precisely because it carries four iodine atoms in its structure — two iodine atoms on each of its two aromatic rings, positioned ortho to the diaryl ether linkage, together with a phenolic on one ring and an amino-acid (alanine-type,

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Question ID VK-148152