JEE Main Chemistry question
How many of the numbered locations in the histidine molecule (shown, with the imidazole ring and -amino group numbered) will form an ion in strongly acidic medium?
Answer: 2
Solution
In strongly acidic medium, only those nitrogen atoms whose lone pair is freely available for protonation (i.e. not already tied up in resonance delocalisation within the aromatic imidazole ring) will actually pick up a proton to form a cationic
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