NEET 2006 Biology question

Which antibiotic inhibits interaction between tRNA and mRNA during bacterial protein synthesis ?

(1)Erythromycin
(2)NeomycinCorrect
(3)Streptomycin
(4)Tetracycline

Answer: (2)

Solution

Several antibiotics act on bacterial (70S) ribosomes. The aminoglycosides, neomycin and streptomycin, bind the 30S subunit and interfere with the correct codon-anticodon (mRNA-tRNA) interaction, causing misreading of mRNA and inhibiting protein synthesis; the key of this question gives

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Question ID VK-089656