NEET 2007 Biology question
During transcription, RNA polymerase holoenzyme binds to a gene promoter and assumes a saddle - like structure. What is it's DNA-binding sequence?
Answer: (1)
Solution
In eukaryotic promoters the RNA polymerase II holoenzyme, with its general transcription factors (TFIID binds first), binds at the TATA box (consensus TATAAA), located about 25-30 bp upstream of the start
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