NEET 2019 Biology question

Under which of the following conditions will there be no change in the reading frame of following mRNA?

(1)Insertion of G at 5th position
(2)Deletion of G from 5th position
(3)Insertion of A and G at 4th and 5th positions respectively
(4)Deletion of GGU from 7th, 8th and 9th positionsCorrect

Answer: (4)

Solution

The reading frame is shifted by the insertion or deletion of any number of bases that is not a multiple of three (frameshift mutation); insertion or deletion of three bases (or a multiple of three) keeps the downstream frame intact. The mRNA is read as AAC AGC GGU GCU AUU. (1) Insertion of one

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Question ID VK-092546