NEET Biology question
Consider the following statements (I-IV) about DNA replication. I. A single origin of replication is used by all organisms, prokaryotic and eukaryotic alike. II. DNA polymerase can add new nucleotides only to a free 3'-OH end of a growing strand. III. The leading strand of the replication fork is synthesised discontinuously as Okazaki fragments. IV. DNA replication is semi-conservative, so each daughter DNA molecule has one parental strand and one newly synthesised strand. Which of the above statements are correct?
Solution
Statement I is false because, unlike prokaryotes (which typically have a single origin of replication), eukaryotic chromosomes have multiple origins of replication; Statement III is false because it is the lagging strand, not the leading strand, that is synthesised discontinuously as
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